Research Article
Research on the Impact and Mechanism for the Inhibition of Micrococcus Catalase Activity by Typical Tetracyclines
Table 2
Combination area ratio and energy change for TC-CAT complexes at different combination sites.
| TCs | Combination area ratio for catalytic active center | Combination area ratio for noncatalytic active center | Energy change for catalytic active center (kcal/mol) | Energy change for noncatalytic active center (kcal/mol) | Combination sites |
| Tetracycline | 58% | 53% | |-5.9784| | |-3.2641| | Catalytic active center | Chlortetracycline | 62% | 57% | |-7.9117| | |-4.8341| | Oxytetracycline | 58% | 56% | |-6.9473| | |-4.5725| | Doxycycline | 55% | 53% | |-3.5510| | |-3.3425| |
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