Research Article

Hematologic Features of Children and Adolescent Patients with Acute Hypersensitivity Reactions on Drugs and Food

Table 1

Clinical characteristics of the patients. The data are presented as group fraction (%) and the absolute values (in parentheses). The 95% confidence limits for the sampled values are given in brackets.

Group of patientsStatisticsa
FH groupDH group

Number of patients5972
Boys3733χ 2 = 3.71,
Girls2239
Age (years)8.31 [7.34; 9.27]8.18 [7.17; 9.18]t = 0.18,
W = 2038.5,
Age (month)106.0 [94.27; 117.7]103.2 [91.1; 115.2]t = 0.33,
W = 2015.0,

Prescribed therapy
Glucocorticosteroids dose (mg/kg per day)2.18 [1.90; 2.46]2.57 [1.95; 3.19]t = –1.16;
W = 1686;
Clinical syndromes
Urticaria only37.3% (22/59)30.6% (22/72)Z = 0.63,
Urticaria + Quincke’s edema40.7% (24/59)23.6% (17/72)Z = 1.9,
Quincke’s edema only3.4% (2/59)0.0% (0/72)
Other skin rashes only13.6% (8/59)20.8% (15/72)Z = 0.86,
Other skin rashes + Quincke’s edema5.1% (3/59)18.1% (13/72)Z = 1.99,
Anaphylaxis0.0% (0/59)6.9% (5/72)
Urticaria BceΓo78.0% (46/59)54.2% (39/72)Z = 2.7,
Other skin rashes BceΓo18.6% (11/59)38.9% (28/72)Z = 2.33,

aStatistical criteria: t: Student’s t-test; KWT: Kruskal-Wallis Test; χ2: Pearson’s chi-square with Yates correction.