Research Article

Simulating Notch-Dome Morphology of Action Potential of Ventricular Cell: How the Speeds of Positive and Negative Feedbacks on Transmembrane Voltage Can Influence the Health of a Cell?

Figure 1

(a) A typical morphology of ventricular AP with five distinct phases and spike-notch-dome (SND) as a significant part of an AP [2]; (b) membrane voltage of a cell can be modeled by a capacitor that is charged by ionic currents.
(a)
(b)