Nephroprotective Role of Zhibai Dihuang Wan in Aristolochic Acid-Intoxicated Zebrafish

<div>Malformation rates of kidney-defective phenotypes of zebrafish embryos after prevention of ZDW. Malformation rates of Tg(<i>wt1b</i>:EGFP) embryos after exposure to different doses of ZDW ((a): 1000 ppm; (b): 500 ppm; (c): 100 ppm) in combination with or without 3 ppm of AA were calculated. Malformation rates for each treatment group were calculated at 48 hpf. The cotreatment group (V) was only applied in low-dose ZDW (100 ppm).</div>

BioMed Research International

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Figure 4: Nephroprotective Role of Zhibai Dihuang Wan in Aristolochic Acid-Intoxicated Zebrafish 