Clinical Study
A Novel Diagnostic Nomogram for Noninvasive Evaluating Liver Fibrosis in Patients with Chronic Hepatitis B Virus Infection
Table 5
Comparing AUROC values of different models.
| | AUROC | SE | | 95% CI for AUROC | | | Lower | Upper |
| Training dataset | | | | | | | | APRI scoring model | 0.722 | 0.028 | <0.001 | 0.668 | 0.777 | 31.02 | <0.001 | FIB-4 scoring model | 0.729 | 0.027 | <0.001 | 0.677 | 0.781 | 24.63 | <0.001 | APAG model | 0.800 | 0.025 | <0.001 | 0.752 | 0.848 | 7.79 | 0.005 | S-index model | 0.770 | 0.025 | <0.001 | 0.721 | 0.819 | 13.21 | <0.001 | The nomogram | 0.857 | 0.021 | <0.001 | 0.816 | 0.899 | — | — | Validation dataset | | | | | | | | APRI scoring model | 0.687 | 0.044 | <0.001 | 0.600 | 0.773 | 19.96 | <0.001 | FIB-4 scoring model | 0.749 | 0.042 | <0.001 | 0.668 | 0.831 | 7.56 | 0.006 | APAG model | 0.791 | 0.038 | <0.001 | 0.717 | 0.865 | 4.53 | 0.033 | S-index model | 0.772 | 0.039 | <0.001 | 0.695 | 0.848 | 5.61 | 0.018 | The nomogram | 0.862 | 0.031 | <0.001 | 0.801 | 0.922 | | |
|
|
The four serological diagnostic models are formulated as follows [ 4– 7]: , , , , and . |