Review Article

Prognostic Role of Optic Nerve Sheath Diameter for Neurological Outcomes in Post-Cardiac Arrest Patients: A Systematic Review and Meta-Analysis

Table 2

Subgroup analysis.

OR (95% CI) ( value)

Sample size
 <60536.76 (12.32–109.66)<0.0010.0% (0.706)
 ≥6035.71 (1.80–18.13)0.00354.7% (0.110)
Study design
 Retrospective55.95 (2.58–13.71)<0.00124.8% (0.256)
 Prospective361.40 (16.26–231.93)<0.0010.0% (0.818)
Cutoff value
 ≤5.5 mm417.86 (4.59–69.54)<0.00151.8% (0.101)
 >5.5 mm416.61 (2.18–126.74)0.00768.5% (0.023)
Time of ONSD measurement
 ≤24 h after ROSC45.78 (2.18–15.28)<0.00137.4% (0.188)
 >24 h after ROSC444.08 (13.60–142.86)<0.0010.0% (0.680)
Method of ONSD measurement
 Computed tomography39.25 (1.28–66.70)<0.00159.6% (0.084)
 Ultrasound522.83 (6.22–83.88)<0.00151.2% (0.085)

CI: confidence intervals; OR: odd ratio; ROSC: return of spontaneous circulation.