Identification and Expression Pattern of EZH2 in Pig Developing Fetuses

Table 1

Subcellular localization of the EZH2 protein predicted by four predictors.

Predictor	Predicated localization	Selected parameters
Euk-mPLoc	Nucleus	Default
CELLO^a	Nucleus (4.750), cytoplasmic (0.133), extracellular (0.052), mitochondrial (0.018), chloroplast (0.013), plasma membrane (0.012), peroxisomal (0.007), ER (0.004), cytoskeletal (0.004), Golgi (0.003), vacuole (0.003), lysosomal (0.002)	Eukaryotes
WoLF PSORT^b	Nucleus (26.0), nucleus and cytoplasmic (15.5), cytoplasmic (3), mitochondria (2), plastid (1)	Animal
TargetP^c	mTP (0.139), SP (0.035), other (0.886)	Nonplant; No cutoff set

^aOutput results in SVM score. ^b32 nearest neighbors are used for this prediction and 26 of them indicated that EZH2 was located in the nucleus. ^cReliability class from 1 to 5 was used to score the prediction accuracy, while 1 indicates the strongest prediction. mTP: mitochondrial targeting peptide; SP: signal peptide.