Expression Atlas of FGF and FGFR Genes in Pancancer Uncovered Predictive Biomarkers for Clinical Trials of Selective FGFR Inhibitors

Figure 3

Cell lines with high FGFR1/3 expression were more sensitive to PD173074. (a) IC50 values of PD173074 in pancancer. Each box contains 2nd and 3rd quartile data. Whiskers go up to 1.5 times interquartile range (log-transformed). (b, c) Cell lines with RUNX1 mutation were more sensitive to PD173074. (d–h) FGFR1 or 3 expression was significantly correlated with IC50 values of PD173074.

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