Decreased ALKBH5, FTO, and YTHDF2 in Peripheral Blood Are as Risk Factors for Rheumatoid Arthritis

Figure 3

Correlation of the mRNA expression of fat mass and obesity-associated protein (FTO) and YT521-B homology domains 2 (YTHDF2) in rheumatoid arthritis (RA) with clinical features. The mRNA expression of FTO in RA positively correlated with disease activity score (DAS28) (a, b) and immunoglobulin G (IgG) (d). The mRNA expression of FTO in RA negatively correlated with complement 3 (C3) (c) and lymphocyte-to-monocyte ratio (LMR) (e). The mRNA expression of YTHDF2 in RA negatively correlated with red blood cell count (RBC) (f), neutrophil percentage (N%) (h), and neutrophil-to-lymphocyte ratio (NLR) (i). The mRNA expression of YTHDF2 in RA positively correlated with lymphocyte percentage (L%) (g) and LMR (j).

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