Construction and Comprehensive Analyses of a Competing Endogenous RNA Network in Tumor-Node-Metastasis Stage I Hepatocellular Carcinoma

Table 2

The top 10 GO terms enrichment for DEmRNAs involved in the ceRNA network using the DAVID database.

GO ID	Term	Genes	Gene count	FDR
GO: 0007049	Cell cycle	KIF23, E2F1, CLSPN, E2F2, PTGS2, E2F7, EZH2, PBK, CEP55, DACH1, CCNB1, CCNE1, SFRP1, RRM2, AXIN2	15	0.000
GO: 0051726	Regulation of cell cycle	KIF23, CCNB1, E2F1, CLSPN, CCNE1, E2F2, PTGS2, SFRP1, E2F7, EZH2, DACH1, AXIN2	12	0.001
GO: 0003006	Developmental process involved in reproduction	CCNB1, PLAG1, PTGS2, SFRP1, E2F7, FOXF2, HOXA10, HOXA9, CBX2, DACH1	10	0.001
GO: 0022414	Reproductive process	E2F1, CCNB1, PLAG1, PROK2, SFRP1, PTGS2, E2F7, FOXF2, HOXA10, HOXA9, CBX2, DACH1, ACSL4	13	0.002
GO: 0000003	Reproduction	E2F1, CCNB1, PLAG1, PROK2, SFRP1, PTGS2, E2F7, FOXF2, HOXA10, HOXA9, CBX2, DACH1, ACSL4	13	0.002
GO: 0010564	Regulation of cell cycle process	KIF23, CCNB1, E2F1, CLSPN, SFRP1, E2F7, EZH2, DACH1, AXIN2	9	0.010
GO: 0022402	Cell cycle process	KIF23, CCNB1, E2F1, CLSPN, CCNE1, E2F7, RRM2, EZH2, PBK, DACH1, CEP55, AXIN2	12	0.015
GO: 0051171	Regulation of nitrogen compound metabolic process	E2F1, PLAG1, E2F2, PTGS2, CPEB3, E2F7, EZH2, ELAVL2, CBX2, DACH1, CCNB1, CCNE1, HOXA3, SFRP1, RRM2, FOXF2, HOXA10, HOXA9, AXIN2, POLQ	20	0.020
GO: 1903047	Mitotic cell cycle process	KIF23, CCNB1, E2F1, CLSPN, CCNE1, E2F7, RRM2, EZH2, PBK, CEP55	10	0.022
GO: 0005667	Transcription factor complex	E2F1, E2F2, E2F7, FOXF2, HOXA10, HOXA9, DACH1	7	0.023

Note: FDR < 0.05. GO: Gene Ontology; DEmRNAs: differentially expressed mRNA; ceRNA: competing endogenous RNA; DAVID: Database for Annotation, Visualization, and Integrated Discovery; FDR: False discovery rates.