Identification of Biomarkers to Construct a Competing Endogenous RNA Network and Establishment of a Genomic-Clinicopathologic Nomogram to Predict Survival for Children with Rhabdoid Tumors of the Kidney
Table 4
Univariate and multivariate Cox regression analyses of overall survival for RTK patients.
Risk factors
Univariate analysis
Multivariate analysis
HR
95% (CI)
value
HR
95% (CI)
value
Age
50
0.9995
0.9987-1
0.268
Gender
Female
24
1
0.233
Male
26
0.6295
0.2942-1.347
Protocol
NWTS-5
13
1
0.522
AREN03B2
37
0.7644
0.336-1.739
Stage
I-II
13
1
0.0248
1
0.11831
III-IV
37
3.9569
1.191-13.15
2.7683
0.7714-9.934
Risk scores based on mRNAs
50
122.5950
23.41-642
17.4276
1.9371-156.792
0.01078
Risk scores based on lncRNAs
50
4.0815
2.227-7.481
1.8739
0.9245-3.798
0.08146
Risk scores based on miRNAs
50
3.6148
1.91-6.84
2.4325
1.2591-4.700
0.00816
HR: hazard ratio; CI: confidence interval; NWTS-5: the fifth National Wilms’ Tumor Study; AREN03B2: clinical trials cooperative group protocol name code.