Combined Administration of Bisphosphonates, Chemotherapeutic Agents, and/or Targeted Drugs Increases the Risk for Stage 3 Medication-Related Osteonecrosis of the Jaw: A 4-Year Retrospective Study

Table 4

The laboratory examination results for the two groups.

Variables	Group A: stage 2 ()		Group B: stage 3 ()		values
		Range		Range
Serum Ca		1.57-2.32		2.02-2.38	0.277
Serum P		0.99-1.46		0.85-1.63	0.654
Serum Mg		0.74-1.15		0.78-1.38	0.323
PTH		9.46-167.34		22.54-80.42	0.720
CRP		0.40-107.00		1.28-184.00	0.844
Calcitonin		0.02-0.68		0.01-0.06	0.286
25-Hydroxy vitamin D		8.17-36.60		6.17-38.20	0.815
Osteocalcin		7.31-41.00		6.63-17.93	0.656
PINP		11.98-136.10		19.76-84.95	0.533
β-CTX		0.12-1.34		0.15-0.60	0.447
ALP		34-93		41-232	0.089

Abbreviations: SD: standard deviation; PTH: parathyroid hormone; CRP: C-reactive protein; PINP: carboxyl-terminal propeptide of type 1 procollagen; β-CTX: beta collagen degradation products; ALP: alkaline phosphatase.