Biomimetic Gold Nanoshell-Loaded Macrophage for Photothermal Biomedicine

Figure 1

(a) Schematic image exhibits the constitution of ANS and ANS-loaded rat alveolar macrophage cells. (b) UV-visible spectrum of ANS, which exhibits a maximum absorption peak at 800–810 nm. And SEM image shows ANS size (152~162 nm) and globular morphology. (c) Phase-contrast microscopic images of empty macrophage and ANS-MAs. The macrophage cells were loaded with ANS by a coculture method for 24 hours (scale bar denotes 100 μm). (d) Holography image of 3D ANS-MAs. Red dots (and red arrow) indicated the ANS location (ANS: gold nanoshell; ANS-MAs: gold nanoshell-loaded macrophages).

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