Licochalcone a Induces ROS-Mediated Apoptosis through TrxR1 Inactivation in Colorectal Cancer Cells

<div>LCA upregulated ROS level and promoted apoptosis through inactivation of the TrxR1 pathway in HCT-116 cells. (a) ROS level was measured using flow cytometry. (b) Cell cycle was detected by flow cytometry. (c) Apoptosis was evaluated using flow cytometry. (d) Apoptosis- and cell cycle-related proteins were detected by western blot. 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BioMed Research International

fig6

Figure 6

Figure 6: Licochalcone a Induces ROS-Mediated Apoptosis through TrxR1 Inactivation in Colorectal Cancer Cells 