BioMed Research International / 2020 / Article / Tab 2

Research Article

Essential Oils of Lemongrass (Cymbopogon citratus Stapf) Induces Apoptosis and Cell Cycle Arrest in A549 Lung Cancer Cells

Table 2

The IC50 values of C. citratus essential oils on various lung cancer cell lines.

Essential oilsa (μg/ml)Wild type of EGFR and TKI-resistanceMutation of EGFR and TKI-resistance
A549H1299H1650H1975

HCL3.84 ± 0.432.45 ± 0.216.24 ± 0.525.36 ± 0.27
HCC3.77 ± 0.283.56 ± 0.406.81 ± 0.756.16 ± 0.54
HLL1.73 ± 0.373.37 ± 0.187.89 ± 0.644.01 ± 0.30
HLC4.50 ± 0.304.94 ± 0.478.71 ± 0.364.25 ± 0.53
LTL4.98 ± 0.685.79 ± 0.276.52 ± 0.294.74 ± 0.07
LTC4.40 ± 0.756.56 ± 0.398.36 ± 0.085.83 ± 0.25
KDL4.25 ± 0.327.50 ± 0.936.15 ± 0.285.46 ± 0.93
KDC5.28 ± 0.598.93 ± 0.504.86 ± 0.298.49 ± 0.68
Camptothecinb0.48 ± 0.020.49 ± 0.050.42 ± 0.010.42 ± 0.05

aExperiments were carried out in triplicate; bpositive control.