Research Article
Citral Induced Apoptosis through Modulation of Key Genes Involved in Fatty Acid Biosynthesis in Human Prostate Cancer Cells: In Silico and In Vitro Study
Table 2
ADMET characteristic of cis-citral and trans-citral.
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Log Po/w: octanol/water partition coefficient; PPB: plasma protein binding (<90% is weakly bound chemicals and >90% is strongly bound chemicals); HIA: human intestinal absorption (0∼20% is poorly absorbed, 20∼70% is moderately absorbed, and 70∼100% is well absorbed); toxicity: rodent carcinogenicity (R: Rat, + is noncarcinogen and–is carcinogen); BBB: blood-brain barrier activity in CNS (>2.0 is high absorption, 2.0 ∼ 0.1 is middle absorption, and <0.1 is low absorption). |