Citral Induced Apoptosis through Modulation of Key Genes Involved in Fatty Acid Biosynthesis in Human Prostate Cancer Cells: In Silico and In Vitro Study

Table 3

Prediction of activity spectra for substances (PASS).

S. no.	Predicted biological activity	P a	P i
1	Apoptosis agonist	0.826	0.006
2	Fatty-acyl-CoA synthase inhibitor	0.784	0.005
3	TP53 expression enhancer	0.747	0.018
4	Farnesyltransferase inhibitor	0.6559	0.002
5	Chemoprotective	0.625	0.004
6	MMP9 expression inhibitor	0.626	0.013
7	HMOX1 expression enhancer	0.616	0.017
8	Transcription factor stimulant	0.590	0.010
9	TNF expression inhibitor	0.590	0.014
10	Transcription factor NF kappa B stimulant	0.590	0.010
11	Immunostimulant	0.608	0.022
12	Lipid metabolism regulator	0.594	0.022
13	Caspase 3 stimulant	0.588	0.018
14	Anticarcinogenic	0.539	0.016
15	HMG CoA synthase inhibitor	0.382	0.004
16	Prostate cancer treatment	0.401	0.022
17	Antioxidant	0.385	0.013