Let-7c-3p Regulates Autophagy under Oxidative Stress by Targeting ATG3 in Lens Epithelial Cells

Figure 3

Let-7c-3p attenuated the autophagy in SRA01/04 cells under oxidative stress. (a) Western blot was used to analyze the expression level of LC3B II and LC3B I proteins in SRA01/04 cells infected by let-7c-3p mimics, let-7c-3p inhibitor, and mimic controls under oxidative stress. (b) The effect of enhanced let-7c-3p on LC3 puncta in SRA01/04 was explored by immunofluorescence. The SRA01/04 cells were treated with 50 μM H₂O₂ for 24 h ().

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