Impact of Prolonged Mechanical Ventilation on Ferroptosis in Renal Ischemia/Reperfusion Injury in Rats

Figure 3

(a–d) Representative electron micrographs of rats in the sham group (a), IRI group (b), IRI+MV-4 h group (c), and IRI+MV-12 h group (d). Sham group: sham operation; IRI group: subjected to 45 min bilateral renal ischemia; IRI+MV-4 h group: subjected to 45 min bilateral renal ischemia and underwent 4-hour MV; IRI+MV-12 h group: subjected to 45 min bilateral renal ischemia and underwent 12-hour MV. IRI: ischemia-reperfusion injury; MV: mechanical ventilation.

(a) Sham group

(b) IRI group

(c) IRI+MV 4h group

(d) IRI+MV 12h group