Antimalarial Properties of Isoquinoline Derivative from Streptomyces hygroscopicus subsp. Hygroscopicus: An In Silico Approach

Figure 3

Binding complex and interaction visualization between adenylosuccinate synthetase (1P9B, blue), hadacidin (HDA, green), and isoquinoline derivative (ISO, yellow). In the ISO-HDA-1P9B binding complex (a), HDA and ISO share the same pocket. Interaction visualization of HDA-1P9B (b) shows it shares some similar residue interactions with ISO-1P9B (c).

(a)

(b)

(c)