Antimalarial Properties of Isoquinoline Derivative from Streptomyces hygroscopicus subsp. Hygroscopicus: An In Silico Approach

Figure 5

Binding complex and interaction visualization between glucose-6-phosphate isomerase (3PR3, grey), fructose-6-phosphate (F6P, green), and isoquinoline derivative (ISO, yellow). In the ISO-F6P-3PR3 binding complex (a), F6P and ISO share the same binding pocket. Interaction visualization of F6P-3PR3 (b) shows it shares some similar residue interactions with ISO-3PR3 (c).

(a)

(b)

(c)