Antimalarial Properties of Isoquinoline Derivative from Streptomyces hygroscopicus subsp. Hygroscopicus: An In Silico Approach

Figure 7

Binding complex and interaction visualization between enoyl-acyl carrier protein reductase (3LT0, orange), 4-(2,4-dichlorophenoxy)-3-hydroxybenzaldehyde (FT1, green), and isoquinoline derivative (ISO, yellow). In the ISO-FT1-3LT0 binding complex (a), FT1 and ISO share the same binding pocket. Interaction visualization of FT1-3LT0 (b) shows it shares some similar residue interactions with ISO—3LT0 (c).

(a)

(b)

(c)