High STRN Expression Promotes HCC Invasion and Migration but Not Cell Proliferation or Apoptosis through Facilitating Epithelial-Mesenchymal Transition

Figure 5

Correlation of STRN expression with E-cadherin and Vimentin expression in human HCC tissues. (a) Representative staining of STRN, E-cadherin, and Vimentin in HCC tissues by immunohistochemical analysis. Images from a low-grade HCC, which exhibits low STRN expression, positive E-cadherin membranous staining, and negative Vimentin expression, and images from a high-grade HCC, which exhibits high STRN expression, reduced E-cadherin membranous staining, and positive Vimentin expression, are shown. Scale bars, 100 μm. (b) STRN expression was negatively correlated with E-cadherin expression but positively correlated with Vimentin expression in HCC tissues, as analysed by Spearman correlation..

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