D-Dimer and Prothrombin Time Are the Significant Indicators of Severe COVID-19 and Poor Prognosis
Table 3
Correlation between the dynamics changes of DD, PT, APTT, Fg, and the prognosis of COVID-19.
Parameters
Outcome at composite endpoint ()
Total
Hospital discharge
Improved
Exacerbation
Death
DD1 ()
<0.55
38
18
4
5
65
0.55-1.11
3
6
0
6
15
>1.11
11
8
4
12
35
Total
52
32
8
23
115
,
,
DD2 ()
<0.55
20
5
0
1
26
0.55-1.11
12
11
0
1
24
>1.11
20
16
8
21
65
Total
52
32
8
23
115
,
,
DD3 ()
<0.55
26
11
0
2
39
0.55-1.10
11
9
0
0
20
>1.10
15
12
8
21
56
Total
52
32
8
23
115
,
,
PT1 ()
<9.2
0
0
0
0
0
9.20-15.0
52
31
6
18
107
>15
0
1
2
5
8
Total
52
32
8
23
115
,
,
PT2 ()
<9.2
0
0
0
0
0
9.20-15.0
50
28
5
13
96
>15
2
4
3
10
19
Total
52
32
8
23
115
,
,
PT3 ()
<9.2
0
0
0
0
0
9.20-15.0
50
30
5
5
90
>15
2
2
3
18
25
Total
52
32
8
23
115
,
,
APTT1 ()
<21.00
0
0
0
2
2
21.00-37.00
27
21
7
11
66
>37.00
25
11
1
10
47
Total
52
32
8
23
115
,
,
APTT2 ()
<21.00
1
1
0
0
2
21.00-37.00
48
29
8
19
104
>37.00
3
2
0
4
9
Total
52
32
8
23
115
,
,
APTT3 ()
<21.00
1
0
0
1
2
21.00-37.00
48
32
7
10
97
>37.00
3
0
1
12
16
Total
52
32
8
23
115
,
,
TT1
<10
0
0
1
0
1
10-20
51
32
7
20
110
>20
1
0
0
3
4
Total
52
32
8
23
115
,
,
TT2
<10
0
0
0
0
0
10-20
52
31
8
20
111
>20
0
1
0
3
4
Total
52
32
8
23
115
,
,
TT3
<10
0
0
0
0
0
10-20
51
32
8
20
111
>20
1
0
0
3
4
Total
52
32
8
23
115
,
,
Fg1 ()
<2.00
1
2
0
4
7
2.00-4.00
19
8
1
6
34
>4.00
32
22
7
13
74
Total
52
32
8
23
115
,
,
Fg2 ()
<2.00
3
1
1
8
13
2.00-4.00
35
20
3
9
67
>4.00
14
11
4
6
35
Total
52
32
8
23
115
,
,
Fg3 ()
<2.00
3
1
2
3
9
2.00-4.00
42
19
3
15
79
>4.00
7
12
3
5
27
Total
52
32
8
23
115
,
,
Normal reference values: DD (<0.55 mg/L); PT (9.20-15 sec); APTT (21.00-37.00 sec); TT (10-20 sec); Fg (2.00-4.00 g/L). value was calculated by a 2-sided test.
