Research Article

Valuable Role of Neutrophil CD64 and Highly Sensitive CRP Biomarkers for Diagnostic, Monitoring, and Prognostic Evaluations of Sepsis Patients in Neonatal ICUs

Table 2

Comparison between EOS and LOS.

Early-onset sepsis group (EOS)Late-onset sepsis group (LOS)
Median (IQR)Median (IQR)

Hb (g/dL)13.5 (11.875-15.275)11.8 (10.1-14.2)-2.3850.017
TLC (×109/L)13.55 (9.05-23.325)15.9 (10.1-20.2)-0.6240.533
ANC (×109/L)8 (3.35-13.675)6.7 (4.25-11.4)-0.3060.76
Platelet (×109/L)218.5 (123-287.25)220.5 (67.75-342.75)-0.3510.725
hs-CRP (mg/L)9 (0-24)24 (6.5-48)-2.9860.003
CD64%0.8725 (0.61575-0.94125)0.8185 (0.54275-0.9275)-0.9970.319
CD64 MFI2.125 (1.6025-2.7075)1.81 (1.32-2.5575)-1.5050.132

Hb: hemoglobin; TLC: total leukocyte count; ANC: absolute neutrophil count; PLT: platelet; hs-CRP: highly sensitive CRP; nCD64%: neutrophil CD64%; nCD64MFI: nCD64 mean fluorescence intensity.