Research Article

Valuable Role of Neutrophil CD64 and Highly Sensitive CRP Biomarkers for Diagnostic, Monitoring, and Prognostic Evaluations of Sepsis Patients in Neonatal ICUs

Table 3

Comparison between nonsurvivor sepsis patients and survivor sepsis patients.

Nonsurvivor sepsis groupSurvivor sepsis group
Median (IQR)Median (IQR)

GA (weeks)34 (32.75-37)36 (34-38)-2.1920.028
BW (grams)2700 (2000-3200)2580 (1900-3212.5)-0.0760.939
Hb (g/dL)11.15 (9.8-12)13.1 (10.675-14.8)-3.507<0.001
TLC (×109/L)10.65 (8.15-17.8)14.6 (9.65-19.95)-2.170.03
ANC (×109/L)6.5 (2.4-12.4)7 (4.4875-12.225)-1.110.267
Platelet (×109/L)90 (29-168)240 (158-321.75)-5.252<0.001
hs-CRP(mg/L)24 (9.75-96)12 (6-37)-2.3680.018
CD64%94.1 (83-97.6)81.85 (60.075-89.375)-4.213<0.001
CD64 MFI2.15 (1.76-3)1.82 (1.44-2.41)-2.9580.003

GA: gestational age; BW: birth weight; Hb: hemoglobin; TLC: total leukocyte count; ANC: absolute neutrophil count; PLT: platelet; hs-CRP: highly sensitive CRP; nCD64%: neutrophil CD64%; nCD64MFI: nCD64 mean fluorescence intensity.