Association of Serum Uric Acid with Metabolic Syndrome and Its Components: A Mendelian Randomization Analysis

Table 2

Association of SLC2A9 (rs11722228) associated with exposures and outcomes.

	Coefficient/HR	95% confidence interval	value
Exposure
Standardized serum uric acid	0.23	(0.14, 0.31)	<0.001
Outcomes
MetS	0.92	(0.62, 1.38)	0.692
Overweight & obesity	0.91	(0.69, 1.21)	0.524
Hyperglycemia	0.97	(0.64, 1.47)	0.896
Hypertension	1.08	(0.84, 1.39)	0.531
Dyslipidemia	1.08	(0.85, 1.36)	0.53

Data are coefficient (95% CI) for association with standardized serum uric acid and hazard ratio (95% CI) for association with outcomes; genotypes under an additive model.