Prognostic Value of Thyroid Hormone FT3 in General Patients Admitted to the Intensive Care Unit

Table 4

Univariable and multivariable logistic regression analyses for 28d mortality.

	Univariable			Multivariable
	OR	95% CI	value	OR	95% CI	value
NTIS	3.531	(1.68, 7.41)	0.001	2.966	(1.272, 6.915)	0.012
FT3	0.433	(0.26, 0.722)	0.001
FT4	1.01	(0.941, 1.083)	0.789
FT4/FT3	1.426	(1.121, 1.814)	0.004
TSH	0.837	(0.585,1.197)	0.329
APACHE II	1.231	(1.160, 1.308)	<0.001
SOFA	1.378	(1.248, 1.520)	<0.001
The duration of MV (h)	1.002	(1.000, 1.003)	0.046
Lactic acid (mmol/L)	1.03	(0.991, 1.072)	0.137
CREA (μmol/L)	1.005	(1.002, 1.007)	<0.001
Oxygenation index	0.995	(0.992, 0.998)	0.003	0.995	(0.991, 0.999)	0.007
WBC	1.121	(1.062, 1.183)	<0.001	1.118	(1.052, 1.187)	<0.001
ALB	0.962	(0.925, 1.000)	0.049	1.004	(1.002, 1.007)	0.001
Age (years)	1.045	(1.016, 1.075)	0.002
BNP	1.001	(1.000, 1.001)	0.003

Variables included in the multivariable logistic analysis were NTIS, the duration of MV, CREA, oxygenation index, WBC, ALB, and age. NTIS: nonthyroidal illness syndrome; FT3: free triiodothyronine; FT4: free thyroxine; TSH: thyroid-stimulating hormone; APACHE II score: acute physiology and chronic health evaluation II score; SOFA: sequential organ failure score; MV: mechanical ventilation; CREA: creatinine; WBC: white blood cell; ALB: albumin; BNP: brain natriuretic peptide.