Research Article
Fractionated Stereotactic Radiation Therapy Using Volumetric Modulated Arc Therapy in Patients with Solitary Brain Metastases
| Adverse events | Grade 1 | Grade 2 | Grade 3 | Grade 4 |
| Nausea | 5 (11%) | 4 (9%) | 0 | 0 | Cognitive disturbance | 5 (11%) | 6 (13%) | 2 (4%) | 0 | Fatigue | 4 (9%) | 2 (4%) | 2 (4%) | 0 | Vomiting | 5 (11%) | 3 (7%) | 0 | 0 | Dermatitis radiation | 1 (2%) | 0 | 0 | 0 | Hearing impairment | 4 (9%) | 3 (7%) | 0 | 0 | Seizure | 3 (7%) | 0 | 1 (2%) | 0 | Increased alanine aminotransferase | 3 (7%) | 1 (2%) | 0 | 0 | Anaemia | 1 (2%) | 0 | 0 | 0 | Hyponatraemia | 1 (2%) | 0 | 0 | 0 | Hypotension | 2 (4%) | 0 | 0 | 0 | Meningitis | 0 | 0 | 0 | 0 | Depression | 2 (4%) | 0 | 0 | 0 | Thrombocytopenia | 0 | 0 | 0 | 0 | Neutropenia | 4 (9%) | 0 | 0 | 0 | Headache | 2 (4%) | 1 (2%) | 0 | 0 | Intracranial haemorrhage | 0 | 0 | 0 | 0 | Central nervous system necrosis | 0 | 0 | 0 | 0 |
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A total of 46 cases of patients were evaluated.
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