Bioactivity and Molecular Docking Studies of Derivatives from Cinnamic and Benzoic Acids

Table 2

Summary of the docking of compound 7 to its potential targets.

Target	Conformer	CHEMPLP		GoldScore		ChemScore		ASP		Consensus -score
		Score	-score	Score	-score	Score	-score	Score	-score
L-14a-D	1	57.54	2.50	27.21	3.21	22.96	0.38	29.54	1.07	1.79
	2	57.48	2.48	16.56	-0.65	27.95	2.19	30.58	1.43	1.36
C-8-SI	1	41.59	2.47	19.52	1.10	17.84	1.70	23.81	0.53	1.45
	2	39.73	1.63	19.58	1.13	16.54	1.00	24.04	0.66	1.11
	3	35.42	-0.31	21.05	1.76	16.46	0.96	26.24	1.90	1.08
TS	1	39.90	3.70	35.31	3.59	9.06	0.06	21.88	0.82	2.04
	2	34.46	1.46	22.10	1.01	11.61	2.14	22.60	1.05	1.41
PO	1	55.61	2.02	35.42	2.55	20.19	1.47	38.76	1.34	1.85
	2	55.82	2.09	30.74	1.22	18.19	0.66	39.43	1.51	1.37
QR	1	36.26	0.33	25.83	1.60	15.48	0.15	21.28	2.56	1.16
	2	36.72	0.49	24.02	1.25	20.01	2.69	16.54	-0.10	1.08
ST-PK	1	57.16	3.64	31.30	3.12	22.65	2.77	26.88	2.59	3.03
CA	1	45.04	2.71	32.49	0.34	14.39	0.32	17.80	0.28	0.91