KIF3C Promotes Proliferation, Migration, and Invasion of Glioma Cells by Activating the PI3K/AKT Pathway and Inducing EMT

<div>KIF3C promotes U87 and U251 cell migration, invasion, and proliferation and suppresses cell apoptosis <i>in vitro</i>. (a, b) Migration and (c, d) invasion of each cell line were evaluated by the transwell assay. The left panels show photos of representative fields (100x magnification), and the right panels show histograms of the results. (e, f) Proliferation was determined at the indicated time intervals using the Cell Counting Kit-8 reagent. (g, h) Cell apoptosis was measured using the annexin V-FITC/PI apoptosis detection kit. 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BioMed Research International

fig2

Figure 2

Figure 2: KIF3C Promotes Proliferation, Migration, and Invasion of Glioma Cells by Activating the PI3K/AKT Pathway and Inducing EMT 