3D Culture System for Liver Tissue Mimicking Hepatic Plates for Improvement of Human Hepatocyte (C3A) Function and Polarity

Figure 5

Quantification of hepatocyte functional gene expression levels: comparison of gene expression associated with liver detoxification and metabolism (a–f), ammonia metabolism and clearance (g, h), protein metabolism (i–l), and coagulation function (m–o). The data are presented as . Two-way ANOVA: comparison between H and other groups: , , . H: hepatic plate-mimetic group; M: mixed 3D group; S: sandwich group; P: mixed 2D/plate group.

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