Prelingual Sensorineural Hearing Loss Caused by a Novel GJB2 Dominant Mutation in a Chinese Family

Figure 3

Pathogenic mutation c.205T > C(p.Phe69Leu): (a) chromatograms of c.205 T > C; (b) comparison of amino acid sequences of p.Phe69 among diverse species, showing highly conserved sequences; (c) molecular modeling of wild-type GJB2; (d) molecular modeling of wild-type and mutant GJB2.

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