Prognostic Evaluation for Patients over 45 Years Old with Gallbladder Adenocarcinoma Resection: A SEER-Based Nomogram Analysis

Table 1

Clinical and pathological features of patients with gallbladder adenocarcinoma over 45 years old.

Variable	Variable level		Training cohort	Validation cohort	value
		()	()	()
		(%)	(%)	(%)
Age	<65	543 (33.7)	412 (34.0)	131 (32.8)	0.648
	≥65	1069 (66.3)	800 (66.0)	269 (67.2)
Marital status	Married	895 (55.5)	675 (55.7)	220 (55.0)	0.809
	Unmarried	717 (44.5)	537 (44.3)	180 (45.0)
Race	White	1213 (75.2)	917 (75.7)	296 (74.0)	0.362
	Black	194 (12.0)	138 (11.4)	56 (14.0)
	Other	205 (12.7)	157 (13.0)	48 (12.0)
Sex	Male	492 (30.5)	381 (31.4)	111 (27.8)	0.165
	Female	1120 (69.5)	831 (68.6)	289 (72.2)
Grade	Well, I	218 (13.5)	166 (13.7)	52 (13.0)	0.692
	Moderately, II	775 (48.1)	580 (47.9)	195 (48.8)
	Poorly, III	596 (37.0)	451 (37.2)	145 (36.2)
	Undifferentiated, IV	23 (1.4)	15 (1.2)	8 (2.0)
AJCC 8^th T stage	T1	150 (9.3)	112 (9.2)	38 (9.5)	0.363
	T2	802 (49.8)	604 (49.8)	198 (49.5)
	T3	602 (37.3)	458 (37.8)	144 (36)
	T4	58 (3.6)	38 (3.14)	20 (5.0)
LODDS	LODDS1	518 (32.1)	397 (32.8)	121 (30.2)	0.648
	LODDS2	642 (39.8)	478 (39.4)	164 (41.0)
	LODDS3	452 (28.0)	337 (27.8)	115 (28.7)
AJCC 8^th M stage	M0	1365 (84.7)	1024 (84.5)	343 (85.8)	0.542
	M1	245 (15.2)	188 (15.5)	57 (14.2)
LN surgery scope	None	40 (2.5)	31 (2.6)	9 (2.3)	0.942
	1 ~ 3	1080 (67.0)	811 (66.9)	269 (67.2)
	4~	492 (30.5)	370 (30.5)	122 (30.5)
Radiation	Yes	385 (23.9)	299 (24.7)	86 (21.5)	0.197
	No/unknown	1227 (76.1)	913 (75.3)	314 (78.5)
Chemotherapy	Yes	678 (42.1)	513 (42.3)	165 (41.2)	0.705
	No/unknown	934 (57.9)	699 (57.7)	235 (58.8)
Tumor size (cm)	<1.9	355 (22.0)	273 (22.5)	82 (20.5)	0.218
	1.9~4.8	895 (55.5)	657 (54.2)	238 (59.5)
	≥4.8	362 (22.5)	282 (23.3)	80 (20.0)

AJCC: American Joint Committee on Cancer; LODDS: log of positive lymph nodes; LN: lymph nodes.