The Course of Circulating Small Extracellular Vesicles in Patients Undergoing Surgical Aortic Valve Replacement

Table 2

Echocardiographic parameters before SAVR, after 7 days and at 3 mo follow-up.

	Pre-SAVR	7 days		3 months
		Mean	value		value
EF (%)			0.9947		0.0719
LVEDd (mm)			0.2511		0.9451
LVESd (mm)			0.9938		0.0194
IVSd (mm)			0.0374		<0.0001
PWd (mm)			0.0049		<0.0001
AWd (mm)			0.0177		<0.0001
Peak gradient (mmHg)			<0.0001		<0.0001
Mean gradient (mmHg)			<0.0001		<0.0001
Peak aortic jet velocity (m/s)			<0.0001		<0.0001
EOA (cm^2)			<0.0001		<0.0001
Indexed EOA (cm^2/m^2 BSA)			<0.0001		<0.0001
Shear stress (Vmax/LV-EF)			<0.0001		<0.0001
Calculated LV-mass (g)			0.0027		0.0006
LV-mass index (g/m^2)			0.0006		0.0002
RWT			0.3011		0.0003

SAVR: surgical aortic valve replacement; EF: ejection fraction; LVEDD: left ventricular end-diastolic diameter; LVESd: left ventricular end-systolic diameter; IVSd: intraventricular septal end-diastolic diameter; PWd: posterior wall diameters; AWd: anterior wall diameter; EOA: effective orifice area; BSA: body surface area; Vmax: peak aortic jet velocity; LV: left ventricular; RWT: relative wall thickness. Significances are expressed vs. baseline parameters before SAVR.