Identification and Characterization of Copy Number-Associated Driver Genes in Esophageal Squamous Cell Carcinoma

Figure 1

The differentially expressed genes and dysregulated pathways in ESCC. (a) The number of upregulated and downregulated genes in ESCC, which are represented by the orange and blue bars, respectively. (b) The ESCC and adjacent normal samples are represented by the nodes colored by red and green, respectively. The - and -axes represent the top two principal components by principal component analysis (PCA). (c) The pathways enriched by the upregulated and downregulated genes. The node size and color represent the number of genes and statistical significance.

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