Suppression of KIF22 Inhibits Cell Proliferation and Xenograft Tumor Growth in Tongue Squamous Cell Carcinoma

Figure 4

Knockdown KIF22 inhibited xenograft tumor growth. (a) Tumor growth curve in nude mice (left). CAL-27 cells and shCAT-27 were injected subcutaneously into the armpit of mice, tumor size was measured every 3 days, and tumor volume was calculated. Representative images of xenograft tumor (right). (b) Protein expression level of KIF22 in xenograft tumor by western blot. (c) Representative images of immunohistochemical staining of KIF22 in xenograft tumors (top) and qualification (bottom).

(a)

(b)

(c)