Antiaging Properties of Exosomes from Adipose-Derived Mesenchymal Stem Cells in Photoaged Rat Skin

Figure 4

Changes in relative expression of type I collagen, type III collagen, MMP-1, and MMP-3 mRNA in the dermis. (a) Real-time PCR showed the relative mRNA expression of collagen I of SD rats exposed to UVB 28 d after ADSC-derived exosome treatment. . . vs. UVB(-) group; ^△ vs. UVB(+) group. (b) Real-time PCR showed the relative mRNA expression of collagen III of SD rats exposed to UVB 28 d after ADSC-derived exosome treatment. . . vs. UVB(-) group; vs. UVB(+) group. (c) Real-time PCR showed the relative mRNA expression of MMP-1 of SD rats exposed to UVB 28 d after ADSC-derived exosome treatment. . . vs. UVB(-) group; vs. UVB(+) group. (d) Real-time PCR showed the relative mRNA expression of MMP-3 of SD rats exposed to UVB 28 d after ADSC-derived exosome treatment. . . vs. UVB(-) group; vs. UVB(+) group.

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