Research Article
miR-155 Knockdown Protects against Cerebral Ischemia and Reperfusion Injury by Targeting MafB
Figure 6
Knockdown of miR-155 relieved ischemia injury in mice with MCAO. (a) miR-155 levels in mouse brain tissues after MCAO by qRT-PCR. (b) MafB protein level in mouse brain tissues after MCAO via immunohistochemistry assay. (c) The expression of IL-1β, IL-6, and TNF-α in mouse brain tissues was determined by ELISA assay. (d) The levels of iNOS and COX-2 in mouse brain tissues were investigated by western blot. (e) Representative images of TTC-stained coronal sections and analysis of the volumes of infarction in mouse brain tissues .
(a) |
(b) |
(c) |
(d) |
(e) |