miR-425-5p Acts as a Molecular Marker and Promoted Proliferation, Migration by Targeting RNF11 in Hepatocellular Carcinoma

Table 1

Correlations between miR-425-5p and clinicopathological features of HCC patients.

Variables	Cases	miR-425-5p expression
		Low ()	High ()
Age (yr)
<50	48	15	33	0.874
≥50	57	17	40
Gender
Male	60	19	41	0.760
Female	45	13	32
Tumor size (cm)
≤5	50	14	36	0.599
>5	55	18	37
AFP (ng/ml)
≤20	38	12	26	0.853
>20	67	20	47
TNM stage
I/II	47	20	27	0.016
III/IV	58	12	46
Liver cirrhosis
Presence	57	19	38	0.488
Absence	48	13	35
HBsAg
Positive	65	21	44	0.603
Negative	40	11	29
Vascular invasion
Presence	55	10	45	0.004
Absence	50	22	28
Multiplicity
Single	42	18	24	0.024
Multiple (≥2)	63	14	49
Intrahepatic metastasis
Presence	52	11	41	0.040
Absence	53	21	32