Research Article
miR-425-5p Acts as a Molecular Marker and Promoted Proliferation, Migration by Targeting RNF11 in Hepatocellular Carcinoma
Table 3
Univariate and multivariate analysis of different prognostic variables influencing DSS in HCC patients.
| Variables | | Univariate analysis | Multivariate analysis model | HR (95% CI) | | HR (95% CI) | |
| Gender | | 0.535 (0.137-1.087) | 0.370 | | | Male | 60 | | | | | Female | 45 | Age (year) | | 0.472 (0.634-1.871) | 0.476 | | | <50 | 48 | | | | | ≥50 | 57 | Tumor size (cm) | | 0.807 (0.934-1.997) | 0.710 | | | ≤5 | 50 | | | | | >5 | 55 | AFP (ng/ml) | | 1.343 (0.841-1.947) | 0.841 | | | ≤20 | 38 | | | | | >20 | 67 | HBsAg | | 1.005 (0.475-2.614) | 0.934 | | | Positive | 65 | | | | | Negative | 40 | TNM stage | | 1.374 (1.057-3.004) | 0.019 | 1.201 (1.847-4.647) | 0.011 | I/II | 47 | | | | | III/IV | 58 | Multiplicity | | 1.340 (0.543-1.670) | 0.012 | 1.284 (0.843-1.842) | 0.015 | Single | 42 | | | | | Multiple (≥2) | 63 | Vascular invasion | | 1.556 (1.706-2.648) | 0.030 | 1.408 (1.641-2.330) | 0.025 | Presence | 55 | | | | | Absence | 50 | Liver cirrhosis | | 1.109 (0.847-1.739) | 0.535 | | | Presence | 57 | | | | | Absence | 48 | Intrahepatic metastasis | | 0.884 (1.045-2.984) | 0.043 | 1.047 (2.034-5.376) | 0.038 | Presence | 52 | | | | | Absence | 53 | miR-425-5p expression | | 1.469 (0.567-1.886) | 0.007 | 1.338 (0.807-2.364) | 0.010 | High | 73 | | | | | Low | 32 |
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HR: hazard rate; CI: confidence interval.
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