Research Article
Integrated Analysis of a Gene Correlation Network Identifies Critical Regulation of Fibrosis by lncRNAs and TFs in Idiopathic Pulmonary Fibrosis
Table 6
Demographic and clinical characteristics of the subjects.
| | Healthy controls | IPF | value | | |
| | Age, mean (SD) | 68.4 (4.7) | 69.0 (6.6) | 0.74 | | Gender, (%) | | | 0.07 | | Male | 11 (55) | 12 (60) | | | Female | 9 (45) | 8 (40) | | | Smoker, (%) | | | 0.001 | | Current | 4 (20) | 2 (10) | | | Former | 7 (35) | 10 (50) | | | Never | 9 (45) | 8 (40) | | | Smoking dose (pack-year) | 37 (14.5-58) | 35.7 (12-56) | 0.14 | | FVC (% predicted), mean (SD) | 96.2 (11.7) | 63.88 (17.0) | <0.01 | | DLCO (% predicted), mean (SD) | 80.8 (17.6) | 42.04 (16.5) | <0.01 | | FEV1 (% predicted), mean (SD) | 106.0 (18.6) | 71.7 (11.0) | <0.001 | | FEV1/FVC (%), mean (SD) | 79.9 (5.0) | 57.8 (8.3) | <0.001 |
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FVC: forced vital capacity; DLCO: diffusing capacity of carbon monoxide; FEV1: forced expiratory volume in one second.
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