Research Article

Altered Gut Microbiota and Shift in Bacteroidetes between Young Obese and Normal-Weight Korean Children: A Cross-Sectional Observational Study

Table 3

Blood biochemical profiles of the participants..

Normal weight ()Obese ()

Glucose (mg/dL)0.027
AST (IU/L)29.0 (25.0; 33.0)25.0 (22.0; 26.0)0.027
ALT (IU/L)13.5 (13.0; 19.0)19.5 (16.0; 29.0)0.018
Total cholesterol (mg/dL)0.165
Triglycerides (mg/dL)47.5 (43.0; 67.0)81.0 (61.0; 132.0)0.003
HDL-cholesterol (mg/dL)0.025
LDL-cholesterol (mg/dL)0.021
hs-CRP (mg/L)0.3 (0.2; 0.4)2.1 (0.7; 3.1)<0.001
Uric acid (mg/L)0.032
Iron (μg/dL)0.353
TIBC (μg/dL)0.115
Transferrin saturation (%)0.212
25-OH vitamin D (ng/mL)0.002
Ferritin (ng/mL)<0.001
Insulin (μU/mL)4.9 (3.8; 6.8)13.8 (9.6; 18.6)<0.001
HOMA-IR1.2 (0.9; 1.8)3.5 (2.4; 4.4)<0.001
HOMA-%B51.5 (43.0; 66.4)122.4 (98.8; 172.9)<0.001
Hemoglobin (g/dL)0.955
HbA1c (%)5.2 (5.1; 5.5)5.3 (5.2; 5.5)0.188
Platelet count (×103/μL)0.567
MPV (fL)7.2 (6.7; 7.3)7.4 (7.1; 8.0)0.017
PDW (%)43.0 (41.2; 51.2)48.0 (44.2; 50.4)0.115
WBC count (×103/μL)0.039
Neutrophil count0.003
Neutrophil (%)0.015
Lymphocyte count (×103/μL)0.911
Lymphocyte (%)0.047
Monocyte count (×103/μL)0.519
Eosinophil count (×103/μL)0.853
Basophil count (×103/μL)0.0 (0.0; 0.0)0.0 (0.0; 0.0)0.474
Neutrophil-to-lymphocyte ratio0.8 (0.7; 1.2)1.2 (1.0; 1.7)0.024

Data are expressed as the , median (interquartile range), or a number (%). Significant values are shown in bold. Abbreviations: AST—aspartate aminotransferase; ALT—alanine aminotransferase; HDL—high-density lipoprotein; LDL—low-density lipoprotein; hs-CRP—high-sensitivity C-reactive protein; TIBC—total iron binding capacity; MPV—mean platelet volume; PDW—platelet distribution width; WBC—white blood cell.