Review Article

The Influence of Diabetes Mellitus on Patients Undergoing Primary Total Lower Extremity Arthroplasty: A Systematic Review and Meta-Analysis

Table 1

Characteristics of the included studies.

Study (year)CountryTypesSample size ()Male (%)Age (y)Surgical methodsNumber of patients (DM/non-DM)Recoded parameters

Adams et al. (2013) [14]USACohort40 49143% in DM and 36% in non-DM68 in DM and 68 in non-DMTKA7567/32924Cardiac disease, kidney disease, DVT, revision, deep infection
Amusat et al. (2014) [15]AustraliaCohort40545% in DM and 37% in non-DM67 in DM and 68 in non-DMTKA60/345Kidney disease,
Bolognesi et al. (2008) [5]USACohort7422363967THA and TKA63461/678775Mortality, DVT
Choong et al. (2007) [16]AustraliaCase-control8194671THA87/732Deep infection
Chun et al. (2014) [17]KoreaCase-control41361% in DM and 58% in non-DM56 in DM and 51 in non-DMTHA41/372Superficial infection
Clement et al. (2013) [18]FranceCohort238944.4% in DM and 42.2% in non-DM70.1 in DM and 70.4 in non-DMTKA275/2114HTN, cardiac disease
Cordero-Ampuero et al. (2010) [19]SpainCase-control124NPNPTHA17/107Superficial infection
Duensing et al. (2019) [20]USACohort7547844.2% in DM and 40.7% in non-DM65.6 in DM and 64.7 in non-DMTKA and THA19854/55624Deep infection
Falcao et al. (2016) [21]USACohort8325% in DM and 37.3% in non-DM72.8 in DM and 64.3 in non-DMTHA24/59Deep infection
Iorio et al. (2012) [22]USACohort4008NRNRTKA and THA331/3677Superficial infection
Jämsen et al. (2012) [23]FinlandCohort71813670.6TKA and THA874/6307Deep infection
Lovecchio et al. (2014) [24]USACohort4329942% in DM and 38.6% in non-DM66 in DM and 68 in non-DMTKA and THA6725/36574HTN, cardiac disease
Maradit Kremers et al. (2017) [25]USACohort1608545.866TKA and THA2911/13147Deep infection
Martinez-Huedo et al. (2013) [27]SpainCohort37313133.3% in DM and 33.8% in non-DM71 in DM and 70% in non-DMTKA and THA40519/332612Mortality,
Martínez-Huedo et al. (2017) [26]SpainCohort7483437.271.5TKA and THA37417/37417Mortality, DVT
Meding et al. (2003) [28]USACohort351948% in DM and 40% in non-DM70 in DM and 70 in non-DMTKA329/4891DVT, deep infection
Moon et al. (2008) [29]KoreaCohort44410.3% in DM and 10.3% in non-DM67.6 in DM and 67.4 in non-DMTKA222/222DVT, superficial infection
Namba et al. (2013) [30]USACase-control562163767.4TKA14432/41784Deep infection
Suzuki et al. (2011) [31]JapanCase-control202212.572TKA276/1746Deep infection
Teo et al. (2018) [32]SingaporeCohort90522% in DM and 21.4% in non-DM67.7 in DM and 65.7 in non-DMTKA123/782HTN, cardiac disease, kidney disease, deep infection
Wang et al. (2013) [33]ChinaCohort24532.1% in DM and 28.6% in non-DM67 in DM and 67.1 in non-DMTKA53/192DVT, HTN, cardiac disease
Webb et al. (2017) [34]USACohort11410240.8% in DM and 36.6% in non-DMNPTKA20248/93854Cardiac disease, cerebrovascular disease, kidney disease
Zhao et al. (2014) [35]ChinaCohort35828.6% in DM and 34.7% in non-DM68.09 in DM and 68.17 in non-DMTKA70/288HTN, DVT

Abbreviations: DM: diabetes mellitus; HTN: hypertension; DVT: deep vein embolization; NP: not provided; TKA: total knee arthroplasties; THA: total hip arthroplasties.