Adverse Drug Reaction due to Antidepressants among Patients with Depression in a Private Psychiatric Hospital of Nepal

Table 3

Antidepressant classes commonly associated with adverse drug reactions.

Drug class	WHO-ATC code	No. of ADRs	ADRs
SSRIs	N06AB	34	Gastritis (5), sedation (4), oral ulcer (3), restlessness (3), erectile dysfunction (2), tremor (2), anxiety (2), insomnia (1), dizziness (1), headache (1), weight gain (3), vomiting (1), abdominal discomfort (1), abdominal distension (1), diarrhea (1), postural hypotension (1), sweating (1), problem with urination (1)
TCAs	N06AA	14	Sedation (3), gastritis (2), weight gain (2), dryness of mouth (2), indigestion (2), blurred vision (1), headache (1), restlessness (1)
Other antidepressants	N06AX	6	Dry mouth (1),weight gain (1), dizziness (1), tremor (1), nausea (1), anxiety (1)

Abbreviation: WHO-ATC: World Health Organization-anatomical therapeutic classification; ADR: adverse drug reaction; SSRIs: selective serotonin reuptake inhibitors; SNRIs: serotonin norepinephrine reuptake inhibitors; TCA: tricyclic antidepressants. Other antidepressants: duloxetine, venlafaxine, bupropion, mirtazapine.