A Selection of Trauma Scores Might Not Correlate with Coagulation Factor Activity following Multiple Injuries: A Retrospective Observational Study from a Level 1 Trauma Center
Table 3
Comparison of clotting factor activities and levels for different regions according to the AIS.
Head
Thorax
Abdomen
Pelvis
Extremities
AIS<3 ()
AIS ≥3 ()
()
()
()
()
()
()
()
()
Fibrinogen (mg/dl)
237 (212-296)
235 (206-268)
.418
237 (213-280)
237 (210-273)
.995
237 (210-275)
228 (134-367)
.754
237 (210-275)
230 (152-268)
.452
237 (216-284)
227 (156-267)
.228
FII (%)
84 (71-97)
73 (65-91)
.201
87 (71-106)
80 (67-92)
.104
81 (68-95)
85 (74-88)
.927
83 (71-95)
50 (44-80)
.021
84 (69-95)
79 (62-96)
.430
Calcium (mmol/l)
2.16 (2.10-2.23)
2.10 (1.96-2.20)
.163
2.16 (1.97-2.25)
2.10 (2.06-2.20)
.582
2.14 (2.06-2.22)
1.93 (1.88-2.14)
.086
2.12 (2.05-2.20)
2.28 (2.07-2.30)
.154
2.14 (2.06-2.20)
2.10 (1.85-2.22)
.193
FV (%)
80 (71-97)
78 (53-90)
.152
90 (70-98)
76 (56-88)
.031
80 (66-96)
77 (68-89)
.658
83 (69-96)
46 (37-73)
.008
80 (67-91)
85 (53-97)
.756
FVII (%)
89 (66-103)
90 (79-100)
.418
90 (74-100)
90 (70-105)
.724
90 (71-102)
91 (64-100)
.735
90 (73-102)
64 (63-92)
.110
90 (73-102)
89 (64-100)
.462
FVIII (%)
231 (138-309)
184 (138-265)
.504
208 (127-317)
207 (140-261)
.780
204 (137-277)
245 (180-325)
.376
208 (136-278)
168 (139-277)
.796
196 (137-268)
258 (135-306)
.363
FIX (%)
95 (81-119)
89 (80-110)
.351
94 (84-120)
94 (77-108)
.379
94 (80-112)
99 (90-120)
.523
94 (82-112)
74 (67-113)
.301
93 (80-113)
97 (79-111)
.739
FX (%)
88 (73-102)
87 (69-94)
.560
90 (73-100)
86 (70-101)
.577
87 (70-100)
90 (75-98)
.764
88 (75-101)
58 (47-91)
.063
89 (70-101)
87 (69-98)
.481
FXI (%)
99 (88-114)
99 (85-117)
.826
106 (88-121)
97 (88-111)
.564
99 (87-116)
99 (88-124)
.938
99 (88-117)
91 (68-118)
.481
99 (88-117)
101 (82-117)
.856
FXII (%)
91 (77-109)
94 (70-112)
.974
91 (70-113)
91 (75-108)
.547
93 (76-111)
80 (62-91)
.216
91 (75-109)
85 (45-116)
.424
91 (77-109)
93 (52-117)
.820
FXIII (%)
88 (73-114)
83 (68-108)
.273
83 (65-115)
89 (76-112)
.217
88 (73-112)
58 (50-102)
.076
87 (73-112)
65 (54-119)
.277
88 (73-113)
79 (62-91)
.141
INR
1.05 (0.99-1.13)
1.08 (1.03-1.18)
.161
1.04 (1.00-1.10)
1.08 (1.01-1.14)
.286
1.06 (1.00-1.13)
1.05 (1.00-1.17)
.938
1.05 (1.00-1.12)
1.13 (1.08-1.25)
.080
1.06 (1.01-1.11)
1.10 (1.00-1.25)
.395
PTT (sec)
24.8 (23.2-27.4)
27.4 (23.5-29.9)
.101
25.3 (23.2-27.8)
25.4 (23.4-28.8)
.598
25.3 (23.3-28.5)
25.7 (23.0-27.6)
.948
25.3 (23.2-28.0)
29.3 (24.0-31.1)
.254
25.4 (23.4-28.0)
24.4 (22.6-29.9)
.808
Hemoglobin (g/dl)
13.0 (11.3-14.2)
12.2 (11.1-13.4)
.175
12.9 (11.2-14.2)
12.8 (11.1-13.9)
.701
13.0 (11.4-14.1)
10.9 (8.9-12.5)
.072
13.0 (11.4-14.0)
11.1 (10.1-13.9)
.397
13.0 (11.4-14.0)
12.1 (9.1-14.0)
.413
PRBC ()
0 (0-1)
0 (0-2)
.880
0 (0-0)
0 (0-3)
.358
0 (0-2)
0 (0-35)
.827
0 (0-0)
3 (1-7)
.007
0 (0-0)
2 (0-5)
.005
FFP ()
0 (0-0)
0 (0-0)
.258
0 (0-0)
0 (0-0)
.944
0 (0-0)
0 (0-41)
.256
0 (0-0)
0 (0-3)
.518
0 (0-0)
0 (0-2)
.117
AIS: Abbreviated Injury Scale; F: clotting factor; INR: International Normalized Ratio; PTT: Partial Thromboplastin Time; PRBC: Packed Red Blood Cells; FFP: Fresh Frozen Plasma. ;; Mann–Whitney-U-Test with median values (25-75 percentiles). Significant results were marked in bold.
