BioMed Research International / 2020 / Article / Tab 1 / Review Article
Effects of ACEIs and ARBs on the Residual Renal Function in Peritoneal Dialysis Patients: A Meta-Analysis of Randomized Controlled Trials Table 1 Characteristics of studies in meta-analysis.
Trials Country Dialysis modality Treatment Sample Age, years Female, SBP mmHg DBP mmHg Baseline RRF Kt/V Urine volume Follow-up, months Dialysis duration, months Guan and Gong 2015 [15 ] China CAPD Telmisartan 27 16 (59.3%) 6 Other active agents# 27 14 (51.9%) 6 Guo and He 2013 [14 ] China PD Valsartan 28 13 (46.4%) 12 Other active agents# 23 10 (43.5%) 12 Jian et al. 2008 [16 ] China PD Valsartan 26 19 (38%) 12 Other active agents# 24 12 Kong et al. 2016 [17 ] China CAPD Irbesartan 17 7 (41.2%) 6 Other active agents# 17 8 (47.1%) 6 Li et al. 2003 [9 ] HK CAPD Ramipril 30 11 (36.7%) 12 Other active agents# 30 11 (36.7%) 12 Qu et al. 2011 [18 ] China PD Benazepril 37 12 Other active agents# 18 12 Reyes-Marin et al. 2012 [19 ] USA APD Enalapril 30 24 (40%) 12 Losartan 30 24 (40%) 12 Historical control group 30 12 Shigenaga et al. 2009 [20 ] Japan CAPD Candesartan/valsartan 30 11 (36.7%) 6 Other active agents# 15 6 Suzuki et al. 2003 [21 ] Japan CAPD Valsartan 14 12 Placebo 10 12 Suzuki et al. 2004 [10 ] Japan CAPD Valsartan 18 3.2 ± 0.3 24 Other active agents# 16 24 Wang and Xiao 2005 [22 ] China CAPD Vaisartan 19 Other active agents# 13 Wang and Ren 2013 [23 ] China CAPD Benazepril 25 12 Other active agents# 25 12 Zhong et al. 2007 [24 ] China PD Irbesartan 26 12 Other active agents# 20 12
Abbreviations: PD: peritoneal dialysis; CAPD: continuous ambulatory peritoneal dialysis; APD: ambulatory peritoneal dialysis.
a Expressed as
or median (range);
If systolic BP was above 140 mmHg in the control group, a calcium antagonist, amlodipine (5 mg once daily), was started, and then the dose was increased up to 10 mg; #Antihypertensive agents were allowed except for ACEIs or ARB treatment.
