The Potential Diagnostic Value of Exosomal Long Noncoding RNAs in Solid Tumors: A Meta-Analysis and Systematic Review

Table 2

The information for the exosome of the included studies.

Author	Year	Isolation method	Exosome content	Content number	Exosomes diameter range(nm)	Median diameter(nm)	Evaluation		Exosome proteins	TEM	NTA
							TEM (nM)	NTA (nM)
Qier L	2014	Total exosome isolation kit	lncRNA	1	30-110	None	Yes	None	None	None	None
Jingting Wang	2014	ExoQuick precipitation kit	lncRNA	1	40-100	None	Yes	None	CD63	/	/
Tong Liu	2016	ExoQuick precipitation kit	lncRNA	1	40-100	100	Yes	None	CD63, Hsp70	None	None
Xianxiu Ge	2017	None	lncRNA	1	30-110	None	Yes	Yes	CD63, CD81	30-150	72.2
Rui Zhang	2017	ExoQuick TC	lncRNA	1	30-120	None	Yes	Yes	CD9, CD63	/	/
Mei Xue	2017	ExoQuick precipitation kit	lncRNA	1	50-200	None	Yes	Yes	CD63, TSG101, Hsp70,Hsp90	50-200	None
Huaying Dong	2018	ExoQuick precipitation kit	lncRNA	1	40-120	100	Yes	Yes	CD63, CD81	None	None
Min Kang	2018	ExoQuick precipitation kit	lncRNA	1	30-100	57.89	Yes	Yes	CD63, CD82	20-200	None
Li Sun	2018	Total exosome isolation kit	lncRNA	1	30-150	None	Yes	None	CD63	None	None
Jiansong Wang	2018	ExoQuick precipitation kit	lncRNA	1	30-150	67.52	Yes	None	TSG101, Hsp70	None	None
Hong Xu	2018	Total exosome isolation kit	lncRNA	1	30-100	None	None	None	None	None	None
Fatemeh Yazarlou	2018	Norgen’s urine exosome RNA isolation kit	lncRNA	4	240	None	None	None	CD63	None	None
Yao Zhan	2018	Urine exosome RNA isolation kit	lncRNA	3	60-150	None	Yes	Yes	CD63, CD81	60-150	20-200
Wei Zhang	2018	ExoQuick precipitation kit	lncRNA	1	30-150	57.89	Yes	None	CD9	20-200	None
Rui Zhao	2018	None	lncRNA	1	50-150	None	Yes	Yes	None	/	/
Rui Zheng	2018	ExoQuick exosome precipitation solution	lncRNA	1	50-120	None	Yes	None	CD63, TSG101	None	None
Yu-Hui Wang	2018	None	lncRNA	2	30-120	None	Yes	None	CD63, TSG101	None	None
Yun Teng	2019	None	lncRNA	1	30-100	None	Yes	None	CD9, CD63	None	None
Shujun Zhang	2019	ExoQuick™ solution	lncRNA	3	100	None	Yes	Yes	CD9, CD63	None	None