Research Article
Risk Factors for Brain Metastases in Patients with Renal Cell Carcinoma
Table 1
Baseline characteristics classified by primary tumor size of renal cell carcinoma.
| | Tumor size | <7 cm | ≥7 cm and <10 cm | ≥10 cm | value |
| | 28793 | 5804 | 4162 | | | Tumor size | | | | <0.001 | | Age | | | | <0.001 | | Age group | | | | <0.001 | | <70 years | 22567 (78.377%) | 4375 (75.379%) | 3351 (80.514%) | | | ≥70 years | 6226 (21.623%) | 1429 (24.621%) | 811 (19.486%) | | | Grade | | | | <0.001 | | Grade I | 3644 (12.656%) | 296 (5.100%) | 128 (3.075%) | | | Grade II | 16578 (57.576%) | 2256 (38.870%) | 1186 (28.496%) | | | Grade III | 7573 (26.302%) | 2333 (40.196%) | 1777 (42.696%) | | | Grade IV | 998 (3.466%) | 919 (15.834%) | 1071 (25.733%) | | | N stage | | | | <0.001 | | N0 | 28485 (98.930%) | 5424 (93.453%) | 3554 (85.392%) | | | N1 | 308 (1.070%) | 380 (6.547%) | 608 (14.608%) | | | M stage | | | | <0.001 | | M0 | 28141 (97.736%) | 4998 (86.113%) | 3050 (73.282%) | | | M1 | 652 (2.264%) | 806 (13.887%) | 1112 (26.718%) | | | Bone metastasis | | | | <0.001 | | No | 28504 (98.996%) | 5570 (95.968%) | 3879 (93.200%) | | | Yes | 289 (1.004%) | 234 (4.032%) | 283 (6.800%) | | | Brain metastasis | | | | <0.001 | | No | 28734 (99.795%) | 5713 (98.432%) | 4061 (97.573%) | | | Yes | 59 (0.205%) | 91 (1.568%) | 101 (2.427%) | | | Liver metastasis | | | | <0.001 | | No | 28727 (99.771%) | 5722 (98.587%) | 3996 (96.012%) | | | Yes | 66 (0.229%) | 82 (1.413%) | 166 (3.988%) | | | Lung metastasis | | | | <0.001 | | No | 28503 (98.993%) | 5301 (91.334%) | 3390 (81.451%) | | | Yes | 290 (1.007%) | 503 (8.666%) | 772 (18.549%) | | | Insurance | | | | <0.001 | | Uninsured | 793 (2.754%) | 197 (3.394%) | 166 (3.988%) | | | Insured | 27636 (95.982%) | 5547 (95.572%) | 3959 (95.123%) | | | Unknown | 364 (1.264%) | 60 (1.034%) | 37 (0.889%) | | | Marital status | | | | 0.095 | | Unmarried | 9743 (33.838%) | 1943 (33.477%) | 1424 (34.214%) | | | Married | 17489 (60.740%) | 3586 (61.785%) | 2541 (61.052%) | | | Unknown | 1561 (5.421%) | 275 (4.738%) | 197 (4.733%) | | | Fuhrman grade | | | | <0.001 | | I | 3631 (12.611%) | 291 (5.014%) | 126 (3.027%) | | | II | 16554 (57.493%) | 2255 (38.853%) | 1174 (28.208%) | | | III | 7558 (26.249%) | 2296 (39.559%) | 1736 (41.711%) | | | IV | 1050 (3.647%) | 962 (16.575%) | 1126 (27.054%) | | | Surgery | | | | <0.001 | | No | 420 (1.459%) | 159 (2.739%) | 165 (3.964%) | | | Partial nephrectomy | 14474 (50.269%) | 425 (7.323%) | 139 (3.340%) | | | Radical nephrectomy | 13899 (48.272%) | 5220 (89.938%) | 3858 (92.696%) | | | Race NEW | | | | <0.001 | | Black | 277 (0.971%) | 52 (0.901%) | 50 (1.210%) | | | Others | 1641 (5.755%) | 342 (5.928%) | 245 (5.929%) | | | Unknown | 3510 (12.310%) | 516 (8.944%) | 429 (10.382%) | | | White | 23086 (80.964%) | 4859 (84.226%) | 3408 (82.478%) | | | T stage NEW | | | | <0.001 | | 1 | 25420 (88.285%) | 548 (9.442%) | 0 (0.000%) | | | 2 | 0 (0.000%) | 2715 (46.778%) | 1570 (37.722%) | | | 3 | 3299 (11.458%) | 2403 (41.402%) | 2293 (55.094%) | | | 4 | 74 (0.257%) | 138 (2.378%) | 299 (7.184%) | |
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