MAGE-Targeted Gold Nanoparticles for Ultrasound Imaging-Guided Phototherapy in Melanoma

Figure 5

Detection of photothermal/ODV efficiency in vivo. (a) Photographs of B16 tumor-bearing mice in the four groups taken during a 15-day period after the various treatments. (b) Ultrasound imaging from the region of interest in B16 tumor-bearing nude mice in the MAGE-Au-PFH-NP group using CEUS after laser irradiation during a 15-day period. (c) Body weight curves (, ) of the four groups after different treatments. (d) Tumor growth curves (, ) of the four groups after various treatments. (e) H&E, TUNEL, and PCNA staining on tumor sections after various treatments. All the scale bars are 50 μm. (The data is shown as , per group; , .).

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